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Chromosome 6 (human)
Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs (the building material of DNA) and represents between 5.5 and 6% of the total DNA in cells. It contains the Major Histocompatibility Complex, which contains over 100 genes related to the immune response, and plays a vital role in organ transplantation.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 2,000 and 2,057 genes.〔(【引用サイトリンク】work=NCBI Map Viewer )〕
As of 2003, the entirety of chromosome 6 has been sequenced by manual annotation of proteins, resulting in the identification of 1,557 genes and 633 pseudogenes.
==Genes==
The human leukocyte antigen lies on chromosome 6 (exception: the gene for β2-microglobulin which is located on chromosome 15), and encodes cell-surface antigen-presenting proteins among other functions. The following are some of the genes and their corresponding Cytogenetic location on chromosome 6:
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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